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Passion fruit juice1/4/2024 Dietary and nutritional approaches are the most paramount modifiable factors in the prevention and management of CVD. Risk factors for CVD include aging, high blood pressure, hypercholesterolemia, and obesity, and are among the most essential contributors to disability-adjusted life years ( Hinton et al., 2018). Large datasets provide insights into the epidemiology of cardiovascular disease (CVD) worldwide, which is the leading cause of disease burden and deaths ( Hinton et al., 2018 India State-Level Disease Burden Initiative CVD Collaborators, 2018). PFJ may be potentially recognized as beverage able to prevent cardiovascular disease. A single administration of PFJ enhanced cardiac autonomic function through augmentation of parasympathetic activity, although it did not attenuate postprandial hyperglycemia. However, there were no significant differences between groups. Blood glucose levels significantly increased at T30 in both PLA ( P=0.00) and PFJ ( P=0.00) groups. Indexes of cardiac autonomic function at T30, including high frequency power ( P=0.03) and total power ( P=0.01), were significantly higher and the ratio of low frequency/high frequency power was significantly lower ( P=0.01) in the PFJ group compared to the PLA group. Short-term heart rate variability and blood glucose levels were evaluated prior to supplementation (T0) and following supplementation for 30, 60, 90, and 120 min (T30, T60, T90, and T120, respectively). Subjects were supplemented with either 50% PFJ, or glucose and fructose solution as a placebo (PLA) at 3.5 mL/kg body mass with a 1-week washout between treatments in a single-dose design. A randomized cross-over trial was conducted in 14 healthy subjects aged 21.29☐.73 years. This study aimed to evaluate the acute effects of passion fruit juice (PFJ) supplementation primarily on cardiac autonomic function and secondary on blood glucose in healthy subjects. Passion fruit is rich in ascorbic acid and potential antioxidants. Ascorbic acid also reduces blood sugar levels and enhances insulin activity, and encourages cardiac autonomic function. Ascorbic acid supplementation provides beneficial effects on enhancing cardiac autonomic function in patients with heart failure.
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